Recovery of integrative central nervous function after one hour global cerebro-circulatory arrest in normothermic cat

@article{Hossmann1987RecoveryOI,
  title={Recovery of integrative central nervous function after one hour global cerebro-circulatory arrest in normothermic cat},
  author={Konstantin Alexander Hossmann and Rainald Schmidt-Kastner and B. Grosse Ophoff},
  journal={Journal of the Neurological Sciences},
  year={1987},
  volume={77},
  pages={305-320}
}
Functional and metabolic recovery of a female cat is described which survived for 1 year following 1 hour global cerebro-circulatory arrest at normothermia. Ischemia was produced by intrathoracal occlusion of the innominate, the left subclavian and both mammary arteries. Following ischemia the animal was kept under intensive care for 46 h. EEG and evoked potentials began to recover after 3 h following ischemia, and spontaneous respiration returned promptly on the 2nd day when the animal was… Expand
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TLDR
The results suggest that prolongation of the duration of ischaemia limits the restoration of the energy state, and the quality of pHi recovery after cerebral ischaemic is affected by the degree of ATP recovery during 60 min of recirculation. Expand
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The high sensitivity of the brain to ischemia is generally attributed to the misrelationship between the high metabolic demands and the low energy reserves of this organ. In fact, complete cessationExpand
The cerebral 'no-reflow' phenomenon after cardiac arrest in rats--influence of low-flow reperfusion.
TLDR
Experimental data indicate that low-flow states following prolonged cardiocirculatory arrest may aggravate early cerebral microcirculatory reperfusion disorders, and Wistar rats did not develop a marked cerebral 'no-reflow' phenomenon after circulatory arrest. Expand
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