Recovery of brightness discrimination in adult rats despite progressive loss of retrogradely labelled retinal ganglion cells after controlled optic nerve crush.

@article{Sautter1993RecoveryOB,
  title={Recovery of brightness discrimination in adult rats despite progressive loss of retrogradely labelled retinal ganglion cells after controlled optic nerve crush.},
  author={J{\"u}rgen Sautter and Bernhard A. Sabel},
  journal={The European journal of neuroscience},
  year={1993},
  volume={5 6},
  pages={680-90}
}
Restoration of brightness discrimination was studied in adult rats after controlled crush of the optic nerve in order to further characterize a recently introduced experimental brain injury model. Mild, moderate or severe crush of the optic nerve produced partial or complete loss of the ability to perform a brightness discrimination task. Two to three weeks following mild injury we observed nearly complete spontaneous behavioural recovery whereas recovery was more limited after moderate and… CONTINUE READING

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