Recovery of alpha-adrenoreceptor mediated responses and binding site number after intravenous benextramine in the rabbit.

Abstract

The densities of [3H]-prazosin and [3H]-clonidine binding sites were determined in spleen and brain membrane preparations from rabbits treated 1 to 48 h previously with benextramine (5 mg/kg). In other rabbits pressor responses to phenylephrine and BHT 920 were examined 1 to 72 h after benextramine administration. After benextramine there was a reduction in… (More)

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@article{Furnace1985RecoveryOA, title={Recovery of alpha-adrenoreceptor mediated responses and binding site number after intravenous benextramine in the rabbit.}, author={Graham Furnace and C. A. Hamilton and J. Leighton Reid and David Sumner}, journal={Journal of autonomic pharmacology}, year={1985}, volume={5 1}, pages={13-7} }