Recovery in humans of intravenously injected isotopic uric acid.


It is presumed that uric acid is an end-product of human metabolism and, as such, is not further catabolized. This presumption is based largely upon indirect evidence such as the failure to demonstrate uricase in human tissues and the uncertain r81e of allantoin in human metabolism. On the other hand, Folin presented evidence that uric acid intravenously… (More)


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