Recovery from a possible cytomegalovirus meningoencephalitis-induced apparent brain stem death in an immunocompetent man: a case report

  title={Recovery from a possible cytomegalovirus meningoencephalitis-induced apparent brain stem death in an immunocompetent man: a case report},
  author={Theresia Monica Rahardjo and Tinni Trihartini Maskoen and Ike Sri Redjeki},
  journal={Journal of Medical Case Reports},
BackgroundRecovery from cytomegalovirus meningoencephalitis with brain stem death in an immunocompetent patient is almost impossible. We present a remarkable recovery from a possible cytomegalovirus infection in an immunocompetent man who had severe neurological syndromes, suggesting brain stem death complicated by pneumonia and pleural effusion.Case presentationA 19-year-old Asian man presented at our hospital’s emergency department with reduced consciousness and seizures following high fever… Expand
3 Citations
Ganciclovir and foscarnet dual-therapy for cytomegalovirus encephalitis: A case report and review of the literature
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Pleural effusions induced by human herpesviruses in the immunocompetent host
Pleural effusions in the immunocompetent host occur in severe viral infections and can be due to comorbidities (or septic complications) or due to the direct HHV pathogenicity although research relative to the susceptibility of pleural mesothelial cells to HHV infection is lacking. Expand
What to exclude when brain death is suspected.
Brain death confounders are infrequently reported and formal studies are lacking, and the importance of identifying pathologies compatible with extensive and irreversible brain damage before proceeding to diagnostic tests should be emphasized. Expand


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Aseptic meningitis: Diagnosis and management
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Viral encephalitis: a clinician’s guide
The Liverpool approach to the investigation and treatment of adults with suspected viral encephalitis is discussed, and the Liverpool algorithm for investigation and Treatment of immunocompetent adults with suspicions of viral encephalitis is introduced. Expand
Cytomegalovirus disease in immunocompetent adults
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Severe cytomegalovirus infection in immunocompetent patients.
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Overview of the diagnosis of cytomegalovirus infection.
Lack of standardized real-time PCR protocols hinders the comparison of data from different centers and the development of uniform guidelines for the management of invasive CMV infections in immunocompromised individuals. Expand
Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection
Despite high seroprevalences in some populations, a substantial percentage of women of reproductive age are CMV seronegative and thus at risk of primary CMV infection during pregnancy, and future vaccine or educational campaigns to prevent primary infection in pregnant women may need to be tailored to suit the needs of different populations. Expand
Cytomegalovirus infection in critically ill patients: a systematic review
CMV infection frequently occurs in critically ill immunocompetent patients and may be associated with poor outcomes and the impact of antiviral agents on clinically meaningful outcomes in these patients is not known. Expand
Cytomegalovirus infection in non-immunosuppressed critically ill patients.
There is a debate if there is a scientific justification for prophylaxis in such immunocompetent patients as those with HIV/AIDS, transplant recipients on immunosuppressive therapy, and malignant hematological disease. Expand