Recovery from a possible cytomegalovirus meningoencephalitis-induced apparent brain stem death in an immunocompetent man: a case report

@article{Rahardjo2016RecoveryFA,
  title={Recovery from a possible cytomegalovirus meningoencephalitis-induced apparent brain stem death in an immunocompetent man: a case report},
  author={Theresia Monica Rahardjo and Tinni Trihartini Maskoen and Ike Sri Redjeki},
  journal={Journal of Medical Case Reports},
  year={2016},
  volume={10}
}
BackgroundRecovery from cytomegalovirus meningoencephalitis with brain stem death in an immunocompetent patient is almost impossible. We present a remarkable recovery from a possible cytomegalovirus infection in an immunocompetent man who had severe neurological syndromes, suggesting brain stem death complicated by pneumonia and pleural effusion.Case presentationA 19-year-old Asian man presented at our hospital’s emergency department with reduced consciousness and seizures following high fever… Expand
3 Citations
Ganciclovir and foscarnet dual-therapy for cytomegalovirus encephalitis: A case report and review of the literature
TLDR
A case of CMV encephalitis in an allogeneic hematopoietic stem cell transplant recipient who received dual antiviral therapy with ganciclovir and foscarnet is described. Expand
Pleural effusions induced by human herpesviruses in the immunocompetent host
TLDR
Pleural effusions in the immunocompetent host occur in severe viral infections and can be due to comorbidities (or septic complications) or due to the direct HHV pathogenicity although research relative to the susceptibility of pleural mesothelial cells to HHV infection is lacking. Expand
What to exclude when brain death is suspected.
TLDR
Brain death confounders are infrequently reported and formal studies are lacking, and the importance of identifying pathologies compatible with extensive and irreversible brain damage before proceeding to diagnostic tests should be emphasized. Expand

References

SHOWING 1-10 OF 27 REFERENCES
Severe Cytomegalovirus Meningitis in an Immunocompetent Patient ; A Case Report
Cytomegalovirus (CMV) is a DNA virus and is a member of the Herpesviridae family. There are few reports of CMV meningitis in immunocompetent adults. We reported an immunocompetent patient presentingExpand
Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review
TLDR
Severe life-threatening complications of CMV infection in immunocompetent patients may not be as rare as previously thought. Expand
Aseptic meningitis: Diagnosis and management
TLDR
Clinical manifestations include headache, fever, malaise, photophobia and meningeal signs, and treatment is mainly supportive except for the nonviral infectious etiology. Expand
Viral encephalitis: a clinician’s guide
TLDR
The Liverpool approach to the investigation and treatment of adults with suspected viral encephalitis is discussed, and the Liverpool algorithm for investigation and Treatment of immunocompetent adults with suspicions of viral encephalitis is introduced. Expand
Cytomegalovirus disease in immunocompetent adults
TLDR
Although limited, current evidence suggests that targeted antiviral therapy with ganciclovir or valganciclovIR is appropriate for severe CMV disease in immunocompetent adults. Expand
Severe cytomegalovirus infection in immunocompetent patients.
TLDR
Although few patients were treated with specific antiviral therapy, five of six patients with severe infection recovered after receiving therapy with ganciclovir or foscarnet, suggesting that rapid diagnosis of CMV disease and early instigation of specific treatment may be important. Expand
Overview of the diagnosis of cytomegalovirus infection.
TLDR
Lack of standardized real-time PCR protocols hinders the comparison of data from different centers and the development of uniform guidelines for the management of invasive CMV infections in immunocompromised individuals. Expand
Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection
TLDR
Despite high seroprevalences in some populations, a substantial percentage of women of reproductive age are CMV seronegative and thus at risk of primary CMV infection during pregnancy, and future vaccine or educational campaigns to prevent primary infection in pregnant women may need to be tailored to suit the needs of different populations. Expand
Cytomegalovirus infection in critically ill patients: a systematic review
TLDR
CMV infection frequently occurs in critically ill immunocompetent patients and may be associated with poor outcomes and the impact of antiviral agents on clinically meaningful outcomes in these patients is not known. Expand
Cytomegalovirus infection in non-immunosuppressed critically ill patients.
TLDR
There is a debate if there is a scientific justification for prophylaxis in such immunocompetent patients as those with HIV/AIDS, transplant recipients on immunosuppressive therapy, and malignant hematological disease. Expand
...
1
2
3
...