The frequency of head and neck cancer is on an ascending path and a lot of cases are discovered in advanced stages. The treatment is difficult and requires the use of reconstructive methods to solve the tissue defects. The authors conducted a retrospective study on 121 cases solved in the ENT Department of "Sf. Spiridon" University Hospital Iaşi hospitalized with oncologic pathology in advanced stages, between 2000-2004. The tissue defects after surgical excision were solved by different types of myocutaneous flaps, necessary to cover or reconstruct visceral or cervicofacial tissue defects. We insisted on difficulties and complications that can appear after this kind of oncological surgery. The results of this study generally prove the usefulness of the myocutaneous flaps in the treatment of the advanced head and neck cancer.