Reconstruction of the evolution of microbial defense systems

  title={Reconstruction of the evolution of microbial defense systems},
  author={Pere Puigb{\`o} and Kira S. Makarova and David M. Kristensen and Yuri I. Wolf and Eugene V. Koonin},
  booktitle={BMC Evolutionary Biology},
Evolution of bacterial and archaeal genomes is a highly dynamic process that involves intensive loss of genes as well as gene gain via horizontal transfer, with a lesser contribution from gene duplication. The rates of these processes can be estimated by comparing genomes that are linked by an evolutionary tree. These estimated rates of genome dynamics events substantially differ for different functional classes of genes. The genes involved in defense against viruses and other invading DNA are… CONTINUE READING
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