Reconstruction of mandibular defects with autogenous bone and decellularized bovine bone grafts with freeze-dried bone marrow stem cell paracrine factors

@inproceedings{Kakabadze2017ReconstructionOM,
  title={Reconstruction of mandibular defects with autogenous bone and decellularized bovine bone grafts with freeze-dried bone marrow stem cell paracrine factors},
  author={Ann Kakabadze and Konstantine Mardaleishvili and George Loladze and Lia Karalashvili and Gocha Chutkerashvili and David Chakhunashvili and Zurab Kakabadze},
  booktitle={Oncology letters},
  year={2017}
}
The gold standard following segmental mandibulectomy is vascularized autologous bone graft in the form of the fibula flap. However, in bone reconstruction the use of autogenous bone does not always guarantee a successful outcome. The aim of the present investigation was to develop a novel biologically active bone (BAB) graft, and to use it for the reconstruction of large size defects of the mandible bone following tumor resection. In the first part of the present study, biologically active bone… CONTINUE READING