Reconstruction of human epidermis on de-epidermized dermis: Expression of differentiation-specific protein markers and lipid composition.

  • Miroslav Ponec
  • Published 1991 in
    Toxicology in vitro : an international journal…


Using the Régnier-Pruniéras method for the reconstruction of epidermis in vitro, a multilayered epidermis was obtained with an overall structure resembling that of native human epidermis. Evaluation of the expression and localization of a number of differentiation-specific protein markers revealed that human epidermis reconstructed on de-epidermized dermis… (More)