Reconstruction of cell population dynamics using CFSE

  title={Reconstruction of cell population dynamics using CFSE},
  author={Andrew Yates and Cliburn Chan and Jessica Strid and Simon Moon and Robin Callard and Andrew J. T. George and Jaroslav Stark},
  journal={BMC Bioinformatics},
Quantifying cell division and death is central to many studies in the biological sciences. The fluorescent dye CFSE allows the tracking of cell division in vitro and in vivo and provides a rich source of information with which to test models of cell kinetics. Cell division and death have a stochastic component at the single-cell level, and the probabilities of these occurring in any given time interval may also undergo systematic variation at a population level. This gives rise to heterogeneity… CONTINUE READING
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