Reconstruction of a probable ancestral form of conger eel galectins revealed their rapid adaptive evolution process for specific carbohydrate recognition.

@article{Konno2007ReconstructionOA,
  title={Reconstruction of a probable ancestral form of conger eel galectins revealed their rapid adaptive evolution process for specific carbohydrate recognition.},
  author={Ayumu Konno and Tomohisa Ogawa and Tsuyoshi Shirai and Koji Muramoto},
  journal={Molecular biology and evolution},
  year={2007},
  volume={24 11},
  pages={2504-14}
}
Recently, many cases of rapid adaptive evolution, which is characterized by the higher substitution rates of nonsynonymous substitutions to synonymous ones, have been identified in the various genes of venomous and biodefense proteins, including the conger eel galectins, congerins I and II (ConI and ConII). To understand the evolutionary process of congerins, we prepared a probable ancestral form, Con-anc, corresponding to the putative amino acid sequence at the divergence of ConI and ConII in… CONTINUE READING
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