Reconstruction of Genuine Pair-Wise Sequence Alignment

Abstract

In many applications, the algorithmically obtained alignment ideally should restore the "golden standard" (GS) alignment, which superimposes positions originating from the same position of the common ancestor of the compared sequences. The average similarity between the algorithmically obtained and GS alignments ("the quality") is an important… (More)
DOI: 10.1089/cmb.2007.0145

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