Reconstruction of Ancestral Protosplice Sites

@article{Sverdlov2004ReconstructionOA,
  title={Reconstruction of Ancestral Protosplice Sites},
  author={Alexander V. Sverdlov and Igor B. Rogozin and Vladimir N. Babenko and Eugene V. Koonin},
  journal={Current Biology},
  year={2004},
  volume={14},
  pages={1505-1508}
}
Most of the eukaryotic protein-coding genes are interrupted by multiple introns. A substantial fraction of introns occupy the same position in orthologous genes from distant eukaryotes, such as plants and animals, and consequently are inferred to have been inherited from the common ancestor of these organisms. In contrast to these conserved introns, many other introns appear to have been gained during evolution of each major eukaryotic lineage. The mechanism(s) of insertion of new introns into… CONTINUE READING
BETA

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 32 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 23 REFERENCES

Wolf for helpful discussions . A novel method for fast and accurate multiple sequence alignment

  • S. Sunyaev, Y.
  • J . Mol . Biol .
  • 2004

Similar Papers

Loading similar papers…