Reconstruction of 4-D Dynamic SPECT Images From Inconsistent Projections Using a Spline Initialized FADS Algorithm (SIFADS)

  title={Reconstruction of 4-D Dynamic SPECT Images From Inconsistent Projections Using a Spline Initialized FADS Algorithm (SIFADS)},
  author={Mahmoud Abdallah and Rostyslav Boutchko and Debasis Mitra and Grant T. Gullberg},
  journal={IEEE Transactions on Medical Imaging},
In this paper, we propose and validate an algorithm of extracting voxel-by-voxel time activity curves directly from inconsistent projections applied in dynamic cardiac SPECT. The algorithm was derived based on factor analysis of dynamic structures (FADS) approach and imposes prior information by applying several regularization functions with adaptively changing relative weighting. The anatomical information of the imaged subject was used to apply the proposed regularization functions adaptively… 

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