Reconstruction, modeling & analysis of Halobacterium salinarum R-1 metabolism.

@article{Gonzalez2008ReconstructionM,
  title={Reconstruction, modeling & analysis of Halobacterium salinarum R-1 metabolism.},
  author={Orland R. Gonzalez and Susanne Gronau and Michaela Falb and Friedhelm Pfeiffer and Eduardo Mendoza and Ralf Zimmer and Dieter Oesterhelt},
  journal={Molecular bioSystems},
  year={2008},
  volume={4 2},
  pages={
          148-59
        }
}
We present a genome-scale metabolic reconstruction for the extreme halophile Halobacterium salinarum. The reconstruction represents a summary of the knowledge regarding the organism's metabolism, and has already led to new research directions and improved the existing annotation. We used the network for computational analysis and studied the aerobic growth of the organism using dynamic simulations in media with 15 available carbon and energy sources. Simulations resulted in predictions for the… CONTINUE READING

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