Reconstruction, modeling & analysis of Halobacterium salinarum R-1 metabolism.

@article{Gonzalez2008ReconstructionM,
  title={Reconstruction, modeling & analysis of Halobacterium salinarum R-1 metabolism.},
  author={O. Gonzalez and S. Gronau and M. Falb and F. Pfeiffer and E. Mendoza and R. Zimmer and D. Oesterhelt},
  journal={Molecular bioSystems},
  year={2008},
  volume={4 2},
  pages={
          148-59
        }
}
  • O. Gonzalez, S. Gronau, +4 authors D. Oesterhelt
  • Published 2008
  • Biology, Medicine
  • Molecular bioSystems
  • We present a genome-scale metabolic reconstruction for the extreme halophile Halobacterium salinarum. The reconstruction represents a summary of the knowledge regarding the organism's metabolism, and has already led to new research directions and improved the existing annotation. We used the network for computational analysis and studied the aerobic growth of the organism using dynamic simulations in media with 15 available carbon and energy sources. Simulations resulted in predictions for the… CONTINUE READING
    65 Citations

    Figures, Tables, and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    Systems Analysis of Bioenergetics and Growth of the Extreme Halophile Halobacterium salinarum
    • 36
    • PDF
    Genome-Scale Metabolic Modeling of Archaea Lends Insight into Diversity of Metabolic Function
    • 13
    • Highly Influenced
    • PDF
    Metabolic reconstruction of the archaeon methanogen Methanosarcina Acetivorans
    • 55
    • PDF
    Constraint-based metabolic modelling of marine microbes and communities.
    • 2

    References

    SHOWING 1-10 OF 65 REFERENCES
    Analysis of Growth of Lactobacillus plantarum WCFS1 on a Complex Medium Using a Genome-scale Metabolic Model*
    • 249
    • PDF
    Genome-scale metabolic model of Helicobacter pylori 26695.
    • 352
    • PDF
    Genome sequence of Halobacterium species NRC-1.
    • W. Ng, S. Kennedy, +40 authors S. Dassarma
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 2000
    • 655
    • PDF
    The Escherichia coli MG1655 in silico metabolic genotype: its definition, characteristics, and capabilities.
    • J. Edwards, B. Palsson
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 2000
    • 896
    • PDF
    Regulation of gene expression in flux balance models of metabolism.
    • 411
    • PDF