Reconstructing immunity after allogeneic transplantation.

  title={Reconstructing immunity after allogeneic transplantation.},
  author={Cynthia R. Giver and Jianming Li and Mohammad Sohrab Hossain and Sagar Lonial and Edmund K Waller},
  journal={Immunologic research},
  volume={29 1-3},
A major goal of our research is to reduce the graft-vs-host disease (GVHD) activity of allogeneic donor T cells in bone marrow transplantation (BMT), while preserving graft-vs-tumor (GVT) effects. Using ex vivo immunosuppressive strategies and cell-separation techniques to modulate the graft prior to transplantation, we examined the roles of different donor… CONTINUE READING