Reconstructing each cell's genome within complex microbial communities—dream or reality?


As the vast majority of microorganisms have yet to be cultivated in a laboratory setting, access to their genetic makeup has largely been limited to cultivation-independent methods. These methods, namely metagenomics and more recently single-cell genomics, have become cornerstones for microbial ecology and environmental microbiology. One ultimate goal is… (More)
DOI: 10.3389/fmicb.2014.00771

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