Reconstitution of carbonic anhydrase activity of the cell-surface-binding protein of vaccinia virus.

@article{Ohradanova2007ReconstitutionOC,
  title={Reconstitution of carbonic anhydrase activity of the cell-surface-binding protein of vaccinia virus.},
  author={Anna Ohradanova and Daniela Vullo and Juraj Kop{\'a}cek and Claudia Temperini and Tatiana Betakova and Silvia Pastorekov{\'a} and Jarom{\'i}r Pastorek and Claudiu T. Supuran},
  journal={The Biochemical journal},
  year={2007},
  volume={407 1},
  pages={61-7}
}
The N-terminal region of a 32 kDa cell-surface-binding protein, encoded by the D8L gene of vaccinia virus, shows sequence homology to CAs (carbonic anhydrases; EC 4.2.1.1). The active CAs catalyse the reversible hydration of CO2 to bicarbonate participating in many physiological processes. The CA-like domain of vaccinia protein [vaccCA (vaccinia virus CA… CONTINUE READING