Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis

Abstract

The tumor microenvironment is critical for metastasis to occur. Subcutaneous xenografts of tumors in immunodeficient mice are usually encapsulated and rarely metastasize as opposed to orthotopic tumors which metastasize if the original tumor was metastatic. In the present report, we were able to reconstitute a metastatic tumor microenvironment by… (More)
DOI: 10.1080/15384101.2017.1281486

Topics

3 Figures and Tables

Slides referencing similar topics