Reconstitution of T-cell function after CD6-depleted allogeneic bone marrow transplantation.

@article{Soiffer1990ReconstitutionOT,
  title={Reconstitution of T-cell function after CD6-depleted allogeneic bone marrow transplantation.},
  author={Robert J. Soiffer and Linda D. Bosserman and Christine Murray and Kenneth W. Cochran and Jamie Daley and Jorge Ritz},
  journal={Blood},
  year={1990},
  volume={75 10},
  pages={
          2076-84
        }
}
Patients who undergo allogeneic bone marrow transplantation (BMT) are clinically immunodeficient for a prolonged period after engraftment. In the present study, we examined immune function after BMT in a series of patients who had received HLA compatible sibling marrow grafts purged of T cells with anti-CD6 monoclonal antibody and complement. None of the patients in this analysis received immunomodulating agents and none had developed graft-versus-host disease (GVHD). Initially after BMT… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 45 references

Activa - tion of natural killer cells via the p 75 interleukin 2 receptor

MA Caligiuri, A Zmuidzinas, +3 authors J Ritz
J Exp Med • 1989

Structural characterization of CD 6 : Properties of two distinct epitopes involved in T cell activation

A Pedrazzini, AS Freedman, +8 authors LM Nadler
Mol Immunol • 1989

The interleukin 2 receptor.

Advances in immunology • 1988