Reconstituted 3-dimensional human skin of various ethnic origins as an in vitro model for studies of pigmentation.

@article{Yoon2003Reconstituted3H,
  title={Reconstituted 3-dimensional human skin of various ethnic origins as an in vitro model for studies of pigmentation.},
  author={Tae-Jin Yoon and Tie Chi Lei and Yuji Yamaguchi and Jan Batzer and Rainer Wolber and Vincent J. Hearing},
  journal={Analytical biochemistry},
  year={2003},
  volume={318 2},
  pages={260-9}
}
Reconstituted 3-dimensional human skin equivalents containing melanocytes and keratinocytes on an artificial dermal substitute are gaining popularity for studies of skin metabolism because they exhibit morphological and growth characteristics similar to human epidermis. In this study, we show that such a pigmented epidermis model can be used to assess the regulation of pigmentation by known melanogenic compounds. In monolayers or in melanocyte-keratinocyte co-cultures, melanocyte-keratinocyte… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Screening of plant extracts for human tyrosinase inhibiting effects.

International journal of cosmetic science • 2012
View 1 Excerpt

Similar Papers

Loading similar papers…