Reconsolidation: the advantage of being refocused

@article{Dudai2006ReconsolidationTA,
  title={Reconsolidation: the advantage of being refocused},
  author={Yadin Dudai},
  journal={Current Opinion in Neurobiology},
  year={2006},
  volume={16},
  pages={174-178}
}
  • Y. Dudai
  • Published 2006
  • Psychology, Medicine
  • Current Opinion in Neurobiology
Ample evidence suggests that upon their retrieval, items in long-term memory enter a transient special state, in which they might become prone to change. The process that generates this state is dubbed 'reconsolidation'. The dominant conceptual framework in this revitalized field of memory research focuses on whether reconsolidation resembles consolidation, which is the process that converts an unstable short-term memory trace into a more stable long-term trace. However, this emphasis on the… Expand
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References

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Rites of Passage of the Engram Reconsolidation and the Lingering Consolidation Hypothesis
TLDR
A framework model is proposed, which interprets reconsolidation as a manifestation of lingering consolidation, rather than recapitulation of a process that had already come to a closure, which reflects on the nature of consolidation in general and makes predictions that could guide further research. Expand
Memory Reconsolidation and Extinction Have Distinct Temporal and Biochemical Signatures
TLDR
The temporal dynamics of memory reconsolidation are dependent on the strength and age of the memory, such that younger and weaker memories are more easily reconsolidated than older and stronger memories. Expand
Protein Synthesis Subserves Reconsolidation or Extinction Depending on Reminder Duration
TLDR
It is shown that re-exposure duration to the learning context acts as a switch guiding the memory course toward reconsolidation or extinction, each depending on protein synthesis. Expand
Stability of Retrieved Memory: Inverse Correlation with Trace Dominance
TLDR
It is reported that in both conditioned taste aversion in the rat and fear conditioning in the medaka fish, the stability of retrieved memory is inversely correlated with the control of behavior by that memory. Expand
The neurobiology of consolidations, or, how stable is the engram?
  • Y. Dudai
  • Psychology, Medicine
  • Annual review of psychology
  • 2004
TLDR
A heated debate has been revitalized on whether memories become labile and must undergo some form of renewed consolidation every time they are activated, and on fundamental issues concerning the nature of the memory trace, its maturation, persistence, retrievability, and modifiability. Expand
Mechanisms of memory stabilization: are consolidation and reconsolidation similar or distinct processes?
  • C. Alberini
  • Medicine, Psychology
  • Trends in Neurosciences
  • 2005
TLDR
A working model is concluded that could explain the apparent controversy of memory vulnerability after reactivation and indicates brain areas involved in consolidation after initial training are not required for reconsolidation. Expand
Characterization of Fear Memory Reconsolidation
TLDR
It is reported that reconsolidation cannot be reduced down to facilitated extinction and application of reminder shock does not result in the reinstatement of the memory, supporting the idea that reactivation of consolidated memories initiates a second time-dependent memory formation process. Expand
Independent Cellular Processes for Hippocampal Memory Consolidation and Reconsolidation
TLDR
By infusing antisense oligodeoxynucleotides into the hippocampus of rats, this work shows that consolidation and reconsolidation are doubly dissociable component processes of memory. Expand
Linking New Information to a Reactivated Memory Requires Consolidation and Not Reconsolidation Mechanisms
TLDR
It is found that reconsolidation does not contribute to the formation of an association between new and reactivated information, and instead, it recruits mechanisms similar to those underlying consolidation of a new memory. Expand
Reconsolidation of fresh, remote, and extinguished fear memory in medaka: old fears don't die
TLDR
It is shown that reconsolidation occurs in fresh long‐term memories but not in remote memories, and that the apparent amnesia induced by blockade of reconsolidations can be reinstated by an unpaired reinforcer, a procedure that has no effect on amnesia inducing by blockade. Expand
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