Reconfiguration dynamics in folded and intrinsically disordered protein with internal friction: Effect of solvent quality and denaturant

@article{Samanta2015ReconfigurationDI,
  title={Reconfiguration dynamics in folded and intrinsically disordered protein with internal friction: Effect of solvent quality and denaturant},
  author={Nairhita Samanta and Rajarshi Chakrabarti},
  journal={Physica A-statistical Mechanics and Its Applications},
  year={2015},
  volume={450},
  pages={165-179}
}

Dispersion Forces and the Molecular Origin of Internal Friction in Protein.

It is concluded that cohesive forces among nonbonded atoms are major contributors to the molecular origin of internal friction.

How does the tail length and the separation between the tagged monomers influence the reconfiguration of a chain with internal friction for different solvent-quality?

Recent experiments involving single proteins have shown the importance of internal friction in protein dynamics. In addition to internal friction, solvent-quality also plays an important role in

Transition between protein-like and polymer-like dynamic behavior: Internal friction in unfolded apomyoglobin depends on denaturing conditions

The dynamics of the acid unfolded and molten globule state are similar in the framework of the Zimm model with internal friction, where the chains still interact and hinder each other: the first Zimm relaxation time is as large as the internal friction time.

How important are fluctuations in the treatment of internal friction in polymers?

The Rouse model with internal friction (RIF), a widely used theoretical framework to interpret the effects of internal friction on conformational transitions in biomolecules, is shown to be an

Chain reconfiguration in active noise

In a typical single molecule experiment, the dynamics of an unfolded protein is studied by determining the reconfiguration time using long-range Förster resonance energy transfer, where the

Rheological consequences of wet and dry friction in a dumbbell model with hydrodynamic interactions and internal viscosity.

The effect of fluctuating internal viscosity and hydrodynamic interactions on a range of rheological properties of dilute polymer solutions is examined using a finitely extensible dumbbell model for

Internal friction can be measured with the Jarzynski equality

A simple protocol for the extraction of the internal friction coefficient of polymers is presented. The proposed scheme necessitates repeatedly stretching the polymer molecule, and measuring the

Low-frequency internal friction behaviour of Zr55Al10Ni5Cu30 metallic glass with different quenching temperatures

The correlation between the internal friction behaviour of Zr55Al10Ni5Cu30 BMG samples and their quenching temperatures was investigated. It was found that, below the glass transition temperature,

Wet and dry internal friction can be measured with the Jarzynski equality

In this work an experimental protocol, based in optical tweezers, is used to measure the internal friction caused by internal interactions in polymers

Effect of internal friction on the coil-stretch transition in turbulent flows.

It is shown that although internal friction does not modify the critical Weissenberg number for the coil-stretch transition, it makes the slope of the probability distribution of the extension steeper, thus rendering the transition sharper.

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