Reconciliation of opposing views on membrane-sugar interactions.

  title={Reconciliation of opposing views on membrane-sugar interactions.},
  author={Heidi Delcomyn Andersen and Chunhua Wang and Lise Arleth and G{\"u}nther H J Peters and Peter Westh},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={108 5},
It is well established that small sugars exert different types of stabilization of biomembranes both in vivo and in vitro. However, the essential question of whether sugars are bound to or expelled from membrane surfaces, i.e., the sign and size of the free energy of the interaction, remains unresolved, and this prevents a molecular understanding of the stabilizing mechanism. We have used small-angle neutron scattering and thermodynamic measurements to show that sugars may be either bound or… CONTINUE READING

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