Recommended tests for association in 2×2 tables

@article{Lydersen2009RecommendedTF,
  title={Recommended tests for association in 2×2 tables},
  author={Stian Lydersen and Morten Wang Fagerland and Petter Laake},
  journal={Statistics in Medicine},
  year={2009},
  volume={28}
}
The asymptotic Pearson's chi‐squared test and Fisher's exact test have long been the most used for testing association in 2×2 tables. Unconditional tests preserve the significance level and generally are more powerful than Fisher's exact test for moderate to small samples, but previously were disadvantaged by being computationally demanding. This disadvantage is now moot, as software to facilitate unconditional tests has been available for years. Moreover, Fisher's exact test with mid‐p… 

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