Recommendations on the use of folic acid supplementation to prevent the recurrence of neural tube defects. Clinical Teratology Committee, Canadian College of Medical Geneticists.

@article{Allen1993RecommendationsOT,
  title={Recommendations on the use of folic acid supplementation to prevent the recurrence of neural tube defects. Clinical Teratology Committee, Canadian College of Medical Geneticists.},
  author={Margot I Van Allen and Frank Clarke Fraser and Louis Dallaire and Judith Md Allanson and D R Mcleod and Eva Andermann and Jan M Friedman},
  journal={CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne},
  year={1993},
  volume={149 9},
  pages={1239-43}
}
OBJECTIVE To prevent the recurrence of neural tube defects (NTDs) in families at increased risk of having offspring with NTDs with the use of periconceptional folic acid supplementation. OPTIONS Genetic counselling and prenatal diagnosis of NTDs. OUTCOMES NTDs cause stillbirth, neonatal death and severe disabilities. The cost for medical care and rehabilitation in the first 10 years of life of a child with spina bifida cystica was estimated to be $42,507 in 1987. EVIDENCE The authors… CONTINUE READING

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