Recommendations of endocrine treatment for patients with gender dysphoria

  title={Recommendations of endocrine treatment for patients with gender dysphoria},
  author={Kevan R Wylie and Robert Fung and Claudia Boshier and Margaret Rotchell},
  journal={Sexual and Relationship Therapy},
  pages={175 - 187}
The purpose of this paper is to provide an objective and independent review of all published papers providing clinical guidelines in the hormonal and medical care of patients with gender dysphoria and transsexualism and to suggest safe modern prescribing guidelines. A computerised search of the published literature was performed using the MEDLINE, EMBASE and PsycINFO databases between 1998 and 2008. In addition, textbooks relating to the subject were reviewed. There are major similarities… 

Coordination of healthcare for transsexual persons: a multidisciplinary approach

The experience in Spain concerning the public healthcare for transsexual persons is described using a multidisciplinary approach and to review the relevant literature.

Good Practice Guidelines for the Assessment and Treatment of Adults with Gender Dysphoria

The Good Practice Guidelines for the Assessment and Treatment of Adults with Gender Dysphoria is a publication of the Intercollegiate Committee of the Royal College of Psychiatrists and recognizes that treatment for gender dysphoria has become more individualized.

IDEA Group Consensus Statement on Medical Management of Adult Gender Incongruent Individuals Seeking Gender Reaffirmation as Female

This consensus statement on medical management provides protocols for the prescribing clinician relating to diagnosis, baseline evaluation and counselling, prescription planning for feminizing hormone therapy and anti-androgen therapy, targets for monitoring hormone therapy, choice of therapy, clinical and biochemical monitoring, recommending sex reaffirmation surgery and peri-operative hormone therapy.

Medical treatment in gender dysphoric adolescents endorsed by SIAMS–SIE–SIEDP–ONIG

The present Position Statement is to develop and adhere to Italian guidelines for treatment of GD adolescents, in line with the “Dutch Approach”, the Endocrine Society (ES), and the World Professional Association for Transgender Health (WPATH) guidelines.

Sexual Dysfunctions and Gender Dysphoria in Women

The chapter deals with female sexual dysfunctions and gender dysphoria/incongruence in women. Concept, classification, clinical presentation, diagnosis and differential diagnosis, and treatment are

The Female-to-Male Medical Treatment

Transsexualism refers to a condition where an individual identifies with a gender that differs from the assigned sex, and treatments need to be customized, as some individuals need cross-sex hormone therapy and surgery to alleviate their gender dysphoria.

Gender dysphoria: treatment and outcomes

Issues facing transgender individuals detained in prison or psychiatric hospital, the factors that affect patients' satisfaction with gender reassignment surgery and how the specialist can ensure a satisfactory outcome are considered.

Medical Treatment for Children with Gender Dysphoria: Conceptual and Ethical Issues

There are various treatment approaches available for children and adolescents with gender identity disorder (GID). This chapter offers an overview of these, with a focus on bringing to light their

“I Couldn’t Imagine My Life Without It”: Australian Trans Women’s Experiences of Sexuality, Intimacy, and Gender-Affirming Hormone Therapy

Despite the increased visibility and knowledge in the area of transgender health, the sexual health and experiences of transgender women undergoing Gender-Affirming Hormone Therapy (GAHT) are still



Endocrinologic treatment of gender identity disorders.

Physicians caring for patients with transsexualism should have a general knowledge about the diagnosis, available treatment, and monitoring for complications of hormonal therapy.

Hormone Treatment of the Adult Transsexual Patient

  • L. Gooren
  • Medicine, Biology
    Hormone Research in Paediatrics
  • 2005
The goal of treatment in female-to-male transsexuals is to induce virilization, including a male pattern of sexual hair, a male voice and male physical contours, and to stop menses.

Endocrine treatment of male-to-female transsexuals using gonadotropin-releasing hormone agonist.

It is concluded that cross-sex hormone treatment of male-to-female transsexuals using GnRHa and oestradiol-17beta valerate is effective, and side effects and complication rates can be reduced using the treatment regimen presented here.

Is physical examination required before prescribing hormones to patients with gender dysphoria?

It is not clear whether or not a physical examination must be performed on all gender dsyphoric patients before prescribing hormones; however, an examination would be helpful in revealing a significant health management issue.

Current management of male-to-female gender identity disorder in the UK

The clinical features, diagnostic approach and management of male-to-female GID in the UK are reviewed, including the behavioural, psychological and surgical aspects.

Multistep treatment concept of transsexual patients.

  • K. SchlattererK. von WerderG. Stalla
  • Medicine, Psychology
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
  • 1996
The importance of an individually designed cross-gender hormone replacement therapy embedded in a multidisciplinary treatment concept, provided by psychiatrists, endocrinologists and surgeons, is demonstrated.

Endocrine Therapy of Transsexualism and Potential Complications of Long-Term Treatment

It is clear that estrogen as well as androgen therapy have a dual role: induction of feminization or virilization and suppression of the hypothalamic-pituitary-gonadal axis leading to a reduction of endogenous estradiol or testosterone secretion.

Physical Aspects of Transgender Endocrine Therapy

This article suggests protocols for the prescribing clinician relating to physical assessment, prescription planning, initiation of endocrine therapy, and ongoing maintenance in transgender adults.

A psycho-endocrinological overview of transsexualism.

The technical possibility of surgical sex change has opened up a debate concerning the legitimacy and utility of carrying out such an intervention at the request of the transsexual. Diagnostic,

Ovarian cancer in female-to-male transsexuals: report of two cases.

Simultaneous salpingo-oophorectomy should be performed in any female-to-male transsexual undergoing hysterectomy in the course of gender-confirming therapy, hypothesized to constitute an additional risk factor in transsexuals as it has been associated with ovarian epithelian cancer.