Recommendations for Management of Clinically Significant Drug-Drug Interactions With Statins and Select Agents Used in Patients With Cardiovascular Disease: A Scientific Statement From the American Heart Association

@article{Wiggins2016RecommendationsFM,
  title={Recommendations for Management of Clinically Significant Drug-Drug Interactions With Statins and Select Agents Used in Patients With Cardiovascular Disease: A Scientific Statement From the American Heart Association},
  author={B. Wiggins and J. Saseen and R. L. Page and Brent N Reed and K. Sneed and J. Kostis and D. Lanfear and S. Virani and P. Morris},
  journal={Circulation},
  year={2016},
  volume={134},
  pages={e468–e495}
}
  • B. Wiggins, J. Saseen, +6 authors P. Morris
  • Published 2016
  • Medicine
  • Circulation
  • A drug-drug interaction (DDI) is a pharmacokinetic or pharmacological influence of 1 medication on another that differs from the known or anticipated effects of each agent alone.1 A DDI may result in a change in either drug efficacy or drug toxicity for 1 or both of the interacting medications.2 Pharmacokinetic DDIs result in altered absorption, distribution, metabolism, or excretion of a medication. [...] Key Method Interpreting this information …Expand Abstract
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