Recombinational histories of avian infectious bronchitis virus and turkey coronavirus

Abstract

Phylogenetic analysis of complete genomes of the avian coronaviruses avian infectious bronchitis (AIBV) and turkey coronavirus (TCoV) supported the hypothesis that numerous recombination events have occurred between these viruses. Although the two groups of viruses differed markedly in the sequence of the spike protein, the gene (S) encoding this protein showed no evidence of positive selection or of an elevated mutation rate. Rather, the data suggested that recombination events have homogenized the portions of the genome other than the S gene between the two groups of viruses, while continuing to maintain the two distinct, anciently diverged versions of the S gene. The latter hypothesis was supported by a phylogeny of S proteins from representative coronaviruses, in which S proteins of AIBV and TCoV fell in the same clade.

DOI: 10.1007/s00705-011-1061-5

8 Figures and Tables

0200400600201220132014201520162017
Citations per Year

546 Citations

Semantic Scholar estimates that this publication has 546 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Hughes2011RecombinationalHO, title={Recombinational histories of avian infectious bronchitis virus and turkey coronavirus}, author={Austin L. Hughes}, journal={Archives of Virology}, year={2011}, volume={156}, pages={1823-1829} }