Recombination within the pandemic norovirus GII.4 lineage.

  title={Recombination within the pandemic norovirus GII.4 lineage.},
  author={John-Sebastian Eden and Mark M. Tanaka and Maciej F. Boni and William D Rawlinson and Peter A White},
  journal={Journal of virology},
  volume={87 11},
Norovirus (NoV) is the leading cause of viral gastroenteritis globally. Since 1996, NoV variants of a single genetic lineage, GII.4, have been associated with at least six pandemics of acute gastroenteritis and caused between 62 and 80% of all NoV outbreaks. The emergence of these novel GII.4 variants has been attributed to rapid evolution and antigenic variation in response to herd immunity; however, the contribution of recombination as a mechanism facilitating emergence is increasingly… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 84 extracted citations


Publications referenced by this paper.
Showing 1-10 of 86 references

Similar Papers

Loading similar papers…