Recombination within the pandemic norovirus GII.4 lineage.

@article{Eden2013RecombinationWT,
  title={Recombination within the pandemic norovirus GII.4 lineage.},
  author={John-Sebastian Eden and Mark M. Tanaka and Maciej F. Boni and William D Rawlinson and Peter A White},
  journal={Journal of virology},
  year={2013},
  volume={87 11},
  pages={6270-82}
}
Norovirus (NoV) is the leading cause of viral gastroenteritis globally. Since 1996, NoV variants of a single genetic lineage, GII.4, have been associated with at least six pandemics of acute gastroenteritis and caused between 62 and 80% of all NoV outbreaks. The emergence of these novel GII.4 variants has been attributed to rapid evolution and antigenic variation in response to herd immunity; however, the contribution of recombination as a mechanism facilitating emergence is increasingly… CONTINUE READING
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