Recombination is proportional to the number of chromosome arms in mammals

  title={Recombination is proportional to the number of chromosome arms in mammals},
  author={Fernando Pardo-Manuel de Villena and Carmen Sapienza},
  journal={Mammalian Genome},
In sexually reproducing organisms recombination contributes significantly to the processes of DNA repair, fidelity of chromosome segregation, and generation of genetic diversity. Abnormal recombination is associated with decreased fitness of offspring, aneuploidy, and several human diseases (Chaganti et al. 1974; Charlesworth and Barton 1996; Hassold et al. 2000). Despite its importance, little is known of how the rate and pattern of recombination is regulated in higher eukaryotes, although sex… CONTINUE READING
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