Recombination in Human Mitochondrial DNA

@article{Wiuf2000RecombinationIH,
  title={Recombination in Human Mitochondrial DNA},
  author={C. Wiuf},
  journal={Science},
  year={2000},
  volume={288},
  pages={1929 - 1929}
}
  • C. Wiuf
  • Published 2000
  • Biology, Medicine
  • Science
The possibility of recombination in human mitochondrial DNA (mtDNA) has been hotly debated over the last few years. In this study, a general model of recombination in circular molecules is developed and applied to a recently published African sample (n = 21) of complete mtDNA sequences. It is shown that the power of correlation measures to detect recombination in circular molecules can be vanishingly small and that the data are consistent with the given model and no recombination only if the… Expand
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  • Proceedings of the National Academy of Sciences of the United States of America
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