Recombination drives genome evolution in outbreak-related Legionella pneumophila isolates

@article{SnchezBus2014RecombinationDG,
  title={Recombination drives genome evolution in outbreak-related Legionella pneumophila isolates},
  author={Leonor S{\'a}nchez-Bus{\'o} and I{\~n}aki Comas and Guillermo Jorques and Fernando Gonz{\'a}lez-Candelas},
  journal={Nature Genetics},
  year={2014},
  volume={46},
  pages={1205-1211}
}
Legionella pneumophila is a strictly environmental pathogen and the etiological agent of legionellosis. It is known that non-vertical processes have a major role in the short-term evolution of pathogens, but little is known about the relevance of these and other processes in environmental bacteria. We report the whole-genome sequencing of 69 L. pneumophila strains linked to recurrent outbreaks in a single location (Alcoy, Spain) over 11 years. We found some examples where the genome sequences… CONTINUE READING
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