Recombination and mammalian genome evolution.

@article{EyreWalker1993RecombinationAM,
  title={Recombination and mammalian genome evolution.},
  author={Adam Eyre-Walker},
  journal={Proceedings. Biological sciences},
  year={1993},
  volume={252 1335},
  pages={237-43}
}
Several lines of evidence are presented which suggest that sequence G + C content and recombination frequency are related in mammals: (i) chromosome G + C content is positively correlated to chiasmata density; (ii) the non-pairing region of the Y chromosome has one of the lowest G + C contents of any chromosomal segment; (iii) a reduction in the rate of recombination at several loci is mirrored by a decrease in G + C content; and (iv) when compared with humans, mice have a lower variance in… CONTINUE READING

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