Recombination Speeds Adaptation by Reducing Competition between Beneficial Mutations in Populations of Escherichia coli

@article{Cooper2007RecombinationSA,
  title={Recombination Speeds Adaptation by Reducing Competition between Beneficial Mutations in Populations of Escherichia coli},
  author={Tim F. Cooper},
  journal={PLoS Biology},
  year={2007},
  volume={5},
  pages={372 - 387}
}
Identification of the selective forces contributing to the origin and maintenance of sex is a fundamental problem in biology. The Fisher-Muller model proposes that sex is advantageous because it allows beneficial mutations that arise in different lineages to recombine, thereby reducing clonal interference and speeding adaptation. I used the F plasmid to mediate recombination in the bacterium Escherichia coli and measured its effect on adaptation at high and low mutation rates. Recombination… CONTINUE READING
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