Recombination Enhances Protein Adaptation in Drosophila melanogaster

  title={Recombination Enhances Protein Adaptation in Drosophila melanogaster},
  author={Daven C Presgraves},
  journal={Current Biology},

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Effects of linkage on rates of molecular evolution.
  • C. BirkyJ. B. Walsh
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1988
Computer simulations and a mathematical argument show that complete linkage to either advantageous or deleterious mutations does not affect the substitution of selectively neutral mutations, However, the simulations show that linkage to selected background mutations decreases the rate of fixation of advantageous mutations and increases the rateof fixation of detrimental mutations.