Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission.

@article{Graham2010RecombinationRA,
  title={Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission.},
  author={Rachel L Graham and Ralph S. Baric},
  journal={Journal of virology},
  year={2010},
  volume={84 7},
  pages={3134-46}
}
Over the past 30 years, several cross-species transmission events, as well as changes in virus tropism, have mediated significant animal and human diseases. Most notable is severe acute respiratory syndrome (SARS), a lower respiratory tract disease of humans that was first reported in late 2002 in Guangdong Province, China. The disease, which quickly spread worldwide over a period of 4 months spanning late 2002 and early 2003, infected over 8,000 individuals and killed nearly 800 before it was… CONTINUE READING
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MINIREVIEW 3143 on N ovem er 12

  • Y. Guan, B. J. Zheng, Y. Q. He, X. L. Liu, Z. X. Zhuang, C. L. Cheung
  • Science
  • 2010
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