Recombinant vaccinia virus primes and stimulates influenza haemagglutinin-specific cytotoxic T cells.

Abstract

The ability of vaccinia virus to accept and express cloned genes encoding immunologically important proteins of unrelated viruses and malarial parasites has suggested a novel approach to the development of live vaccines. Vaccinia virus recombinants retain infectivity and stimulate synthesis of specific antibodies to the cloned gene products in vaccinated… (More)

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@article{Bennink1984RecombinantVV, title={Recombinant vaccinia virus primes and stimulates influenza haemagglutinin-specific cytotoxic T cells.}, author={Jack R.. Bennink and Jonathan W. Yewdell and Geoffrey L Smith and Clemens Moller and Bernard Moss}, journal={Nature}, year={1984}, volume={311 5986}, pages={578-9} }