Recombinant vaccines against ovine footrot.

  title={Recombinant vaccines against ovine footrot.},
  author={T J O'meara and John R Egerton and Herman W. Raadsma},
  journal={Immunology and cell biology},
  volume={71 ( Pt 5)},
For the past 20 years footrot vaccines have evolved from simple bacterins to highly specific recombinant DNA (rDNA) fimbrial vaccines. The development of these vaccines has left a trail of discoveries, challenges and solutions; these processes continue as we move closer to understanding the requirements of a footrot vaccine. The initial whole cell vaccines were unsuccessful due to the short duration of immunity and incorporation of limited serotypes. A multistrain vaccine eliminated the problem… CONTINUE READING