Recombinant spider silk particles as drug delivery vehicles.

@article{Lammel2011RecombinantSS,
  title={Recombinant spider silk particles as drug delivery vehicles.},
  author={Andreas S Lammel and Martin Schwab and Markus Hofer and Gerhard Winter and Thomas Scheibel},
  journal={Biomaterials},
  year={2011},
  volume={32 8},
  pages={2233-40}
}
Spider silk has been in the focus of research mainly due to the superior mechanical characteristics of silk fibers. However, it has been previously shown that spider silk proteins can also adopt other morphologies such as submicroparticles. This study examines the applicability of such particles as drug carriers. Particle characterization revealed that particles made of the engineered spider silk protein eADF4(C16) are colloidally stable in solution. Here, it is shown that small molecules with… CONTINUE READING