Recombinant soluble thrombomodulin for postoperative disseminated intravascular coagulation.

  title={Recombinant soluble thrombomodulin for postoperative disseminated intravascular coagulation.},
  author={Daisuke Hashimoto and Akira Chikamoto and Nobutomo Miyanari and Chitoshi Ohara and Masafumi Kuramoto and Kei Horino and Hisami Ohshima and Hideo Baba},
  journal={The Journal of surgical research},
  volume={197 2},
BACKGROUND Thrombomodulin is a thrombin receptor on the endothelial cell surface that plays an important role in the regulation of intravascular coagulation. The purpose of this study was to evaluate the efficacy and safety of treatment with recombinant human soluble thrombomodulin (rhTM) for patients with septic-disseminated intravascular coagulation (DIC) associated with gastroenterological surgery. MATERIALS AND METHODS From April 2011-September 2013, 201 patients with DIC associated with… CONTINUE READING
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