Recombinant polioviruses expressing hepatitis B virus-specific cytotoxic T-lymphocyte epitopes.

@article{Cho2000RecombinantPE,
  title={Recombinant polioviruses expressing hepatitis B virus-specific cytotoxic T-lymphocyte epitopes.},
  author={Sayeon Cho and B Lee and Mee K. Min},
  journal={Vaccine},
  year={2000},
  volume={18 25},
  pages={2878-85}
}
T-cell immune response to recombinant poliovirus expressing foreign antigens has not been elucidated well. In order to investigate the potential use of poliovirus as a T-cell vaccine vector, we constructed recombinant polioviruses expressing HBV-derived CTL epitopes, HBsAg(28-39) (L(d)-restricted; IPQSLDSWWTSL) and HBc(93-100) (K(b)-restricted; MGLKFRQL) at… CONTINUE READING