Recombinant monoclonal antibodies for rabies post-exposure prophylaxis

@article{Ilina2018RecombinantMA,
  title={Recombinant monoclonal antibodies for rabies post-exposure prophylaxis},
  author={Elena N. Ilina and M. V. Larina and Teimur Aliev and Dmitry A. Dolgikh and Mikhail P. Kirpichnikov},
  journal={Biochemistry (Moscow)},
  year={2018},
  volume={83},
  pages={1-12}
}
Rabies virus is a prototypical neurotropic virus that causes one of the most dangerous zoonotic diseases in humans. Humanized or fully human monoclonal antibodies (mAb) that neutralize rabies virus would be the basis for powerful post-exposure prophylaxis of rabies in humans, having several significant benefits in comparison with human or equine rabies polyclonal immunoglobulins. The most advanced antibodies should broadly neutralize natural rabies virus isolates, bind with conserved antigenic… CONTINUE READING
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