Recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice.

@article{RosbergCody2011RecombinantLE,
  title={Recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice.},
  author={Eva Rosberg-Cody and Catherine Stanton and Liam O'Mahony and Rebecca Wall and F Shanahan and Eamonn M M Quigley and Gerald F. Fitzgerald and R Paul Ross},
  journal={Microbiology},
  year={2011},
  volume={157 Pt 2},
  pages={609-15}
}
We have previously demonstrated that oral administration of a metabolically active Bifidobacterium breve strain, with ability to form cis-9, trans-11 conjugated linoleic acid (CLA), resulted in modulation of the fatty acid composition of the host, including significantly elevated concentrations of c9, t11 CLA and omega-3 (n-3) fatty acids in liver and adipose tissue. In this study, we investigated whether a recombinant lactobacillus expressing linoleic acid isomerase (responsible for production… CONTINUE READING

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