Recombinant human leukocyte interferon-alpha 2b stimulates the synthesis and release of a 90K tumor-associated antigen in human breast cancer cells.

Abstract

We have previously reported the production of a new monoclonal antibody (MAb) (SP-2) recognizing a 90-kDa tumor-associated antigen, termed 90K, which is increased in the serum of many cancer patients. Treatment of CG5 human breast cancer cells with recombinant interferon-alpha 2b (rIFN-alpha 2b) can increase the synthesis and release, in culture medium, of… (More)

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@article{Iacobelli1988RecombinantHL, title={Recombinant human leukocyte interferon-alpha 2b stimulates the synthesis and release of a 90K tumor-associated antigen in human breast cancer cells.}, author={Stefano Iacobelli and Giovanni Scambia and Claudia Natoli and Pierluigi Beneditti Panici and Gian Luca Baiocchi and Laura Perrone and Salvatore Mancuso}, journal={International journal of cancer}, year={1988}, volume={42 2}, pages={182-4} }