Recombinant human lactoferrin induces human and mouse dendritic cell maturation via Toll-like receptors 2 and 4.

@article{Spadaro2014RecombinantHL,
  title={Recombinant human lactoferrin induces human and mouse dendritic cell maturation via Toll-like receptors 2 and 4.},
  author={Michela Spadaro and Monica Montone and Maddalena Arigoni and Daniela Cantarella and Guido Forni and Federica Pericle and Steve Pascolo and Raffaele Adolfo Calogero and Federica Cavallo},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2014},
  volume={28 1},
  pages={416-29}
}
Lactoferrin, a key component of innate immunity, is a cationic monomeric 80-kDa glycoprotein of the transferrin superfamily. Recombinant human lactoferrin, known as talactoferrin (TLF), induces a distinct functional maturation program in human dendritic cells (DCs) derived from peripheral blood monocytes. However, the receptors and molecular mechanisms involved in this induction have not been fully determined. By exploiting genome-wide transcription profiling of immature DCs, TNF-α- and IL-1… CONTINUE READING
9 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…