Recombinant human interleukin 10 for induction of remission in Crohn's disease.

@article{Buruiana2010RecombinantHI,
  title={Recombinant human interleukin 10 for induction of remission in Crohn's disease.},
  author={Felicia Elena Buruiana and Iv{\'a}n Sol{\`a} and Pablo Alonso-Coello},
  journal={The Cochrane database of systematic reviews},
  year={2010},
  volume={11},
  pages={CD005109}
}
BACKGROUND The etiology of Crohn's disease remains unknown, nevertheless, it is apparent that inflammation is associated with an imbalance between proinflammatory and anti-inflammatory cytokines produced within the intestinal mucosa. Crohn's disease represents a state of dysregulated inflammation and drugs that can augment the anti-inflammatory response have the potential to downregulate inflammation and thereby improve the disease. The efficacy of recombinant IL-10 in Crohn's disease was first… CONTINUE READING