Recombinant human interferon gamma therapy for osteopetrosis.


A defect in leukocytic superoxide formation has been demonstrated in patients with congenital osteopetrosis. This leukocyte defect appears to be related to defective bone resorption. Because recombinant human interferon gamma therapy enhances superoxide production in patients with chronic granulomatous disease, we sought to determine whether a similar… (More)


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@article{Key1992RecombinantHI, title={Recombinant human interferon gamma therapy for osteopetrosis.}, author={L. Lyndon Key and William Louis Ries and Ramona Marie Rodriguiz and Heather C. Hatcher}, journal={The Journal of pediatrics}, year={1992}, volume={121 1}, pages={119-24} }