Recombinant human growth hormone modulates Th1 and Th2 cytokine response in burned mice.

@article{Takagi1998RecombinantHG,
  title={Recombinant human growth hormone modulates Th1 and Th2 cytokine response in burned mice.},
  author={K Takagi and Fujio Suzuki and Robert E. Barrow and Steven E. Wolf and David N . Herndon},
  journal={Annals of surgery},
  year={1998},
  volume={228 1},
  pages={106-11}
}
OBJECTIVE To determine whether growth hormone (GH) influences the production of type 1 T-helper (Th1) and type 2 T-helper (Th2) cytokine responses after burn. SUMMARY BACKGROUND DATA GH has been shown to influence immunoregulation. The authors previously reported improved mortality in burned mice treated with GH after infection with herpesvirus. Other work has shown that impaired immunity after burn was characterized by conversion of Th cell populations from Th1 cells to Th2 cells, suggesting… CONTINUE READING

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